LOC101070662 protein (Takifugu rubripes) - STRING interaction network

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LOC101070662

PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (191 aa)

Predicted Functional Partners:

kdr

0.967

vegfb

0.954

vegfa

0.920

flt1

0.917

flt4

0.885

LOC101071220

0.885

pdgfrb

0.852

flt3

0.852

pdgfra

0.852

LOC101080143

0.744

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101070662	LOC101071220	ENSTRUP00000021515	ENSTRUP00000026445	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Kinase insert domain receptor like; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.885
LOC101070662	LOC101080143	ENSTRUP00000021515	ENSTRUP00000006673	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Macrophage colony-stimulating factor 1 receptor 2; Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Promotes reorganization of the [...]	0.744
LOC101070662	flt1	ENSTRUP00000021515	ENSTRUP00000067811	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Uncharacterized protein.	0.917
LOC101070662	flt3	ENSTRUP00000021515	ENSTRUP00000048526	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Fms-related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.852
LOC101070662	flt4	ENSTRUP00000021515	ENSTRUP00000013679	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Fms-related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.885
LOC101070662	kdr	ENSTRUP00000021515	ENSTRUP00000075864	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Kinase insert domain receptor (a type III receptor tyrosine kinase); Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.967
LOC101070662	pdgfra	ENSTRUP00000021515	ENSTRUP00000073047	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for pdgfa, pdgfb and pdgfc and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. Required for normal development of the gastrointestinal tract. Plays a role in cell migration and chemotaxis in wound [...]	0.852
LOC101070662	pdgfrb	ENSTRUP00000021515	ENSTRUP00000018654	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. Required for normal development of the cardiovascular system. Required for normal recruitment of [...]	0.852
LOC101070662	vegfa	ENSTRUP00000021515	ENSTRUP00000077408	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family.	0.920
LOC101070662	vegfb	ENSTRUP00000021515	ENSTRUP00000056656	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	0.954
LOC101071220	LOC101070662	ENSTRUP00000026445	ENSTRUP00000021515	Kinase insert domain receptor like; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	0.885
LOC101071220	pdgfrb	ENSTRUP00000026445	ENSTRUP00000018654	Kinase insert domain receptor like; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. Required for normal development of the cardiovascular system. Required for normal recruitment of [...]	0.720
LOC101071220	vegfa	ENSTRUP00000026445	ENSTRUP00000077408	Kinase insert domain receptor like; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family.	0.929
LOC101071220	vegfb	ENSTRUP00000026445	ENSTRUP00000056656	Kinase insert domain receptor like; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	0.944
LOC101080143	LOC101070662	ENSTRUP00000006673	ENSTRUP00000021515	Macrophage colony-stimulating factor 1 receptor 2; Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Promotes reorganization of the [...]	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	0.744
LOC101080143	vegfa	ENSTRUP00000006673	ENSTRUP00000077408	Macrophage colony-stimulating factor 1 receptor 2; Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Promotes reorganization of the [...]	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family.	0.768
LOC101080143	vegfb	ENSTRUP00000006673	ENSTRUP00000056656	Macrophage colony-stimulating factor 1 receptor 2; Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Promotes reorganization of the [...]	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	0.742
flt1	LOC101070662	ENSTRUP00000067811	ENSTRUP00000021515	Uncharacterized protein.	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	0.917
flt1	pdgfrb	ENSTRUP00000067811	ENSTRUP00000018654	Uncharacterized protein.	Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. Required for normal development of the cardiovascular system. Required for normal recruitment of [...]	0.720
flt1	vegfa	ENSTRUP00000067811	ENSTRUP00000077408	Uncharacterized protein.	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family.	0.929