htr1d protein (Takifugu rubripes) - STRING interaction network

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htr1d

5-hydroxytryptamine receptor 1D; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Regulates the release of 5-hydroxytryptamine in the brain, and thereby affects neural activity. May also play a role in regulating the release of other neurotransmitters. May play a role in vasoconstriction (By similarity). (379 aa)

Predicted Functional Partners:

LOC115250008

0.774

gnb1

0.738

LOC101077498

0.738

LOC101069051

0.738

gnb4

0.738

LOC101074575

0.738

gnb2

0.738

GNG4

0.734

gng2

0.734

LOC101062666

0.723

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GNG4	LOC101062666	ENSTRUP00000063062	ENSTRUP00000069583	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.735
GNG4	LOC101069051	ENSTRUP00000063062	ENSTRUP00000025511	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4.	Guanine nucleotide binding protein (G protein), beta polypeptide 3a.	0.624
GNG4	LOC101074575	ENSTRUP00000063062	ENSTRUP00000070100	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4.	Guanine nucleotide binding protein (G protein), beta 5a.	0.788
GNG4	LOC101077498	ENSTRUP00000063062	ENSTRUP00000019298	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4.	Guanine nucleotide binding protein (G protein), beta 5b.	0.788
GNG4	LOC115250008	ENSTRUP00000063062	ENSTRUP00000057470	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.662
GNG4	gnb1	ENSTRUP00000063062	ENSTRUP00000001674	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4.	Guanine nucleotide binding protein (G protein), beta polypeptide 1a.	0.801
GNG4	gnb2	ENSTRUP00000063062	ENSTRUP00000076510	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4.	Guanine nucleotide binding protein (G protein), beta polypeptide 2.	0.801
GNG4	gnb4	ENSTRUP00000063062	ENSTRUP00000055099	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4.	Guanine nucleotide binding protein (G protein), beta polypeptide 4b.	0.801
GNG4	htr1d	ENSTRUP00000063062	ENSTRUP00000021543	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4.	5-hydroxytryptamine receptor 1D; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Regulates the release of 5-hydroxytryptamine in the brain, and thereby affects neural activity. May also play a role in regulating the release of other neurotransmitters. May play a role in vasoconstriction (By similarity).	0.734
LOC101062666	GNG4	ENSTRUP00000069583	ENSTRUP00000063062	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4.	0.735
LOC101062666	LOC101069051	ENSTRUP00000069583	ENSTRUP00000025511	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide binding protein (G protein), beta polypeptide 3a.	0.775
LOC101062666	LOC101074575	ENSTRUP00000069583	ENSTRUP00000070100	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide binding protein (G protein), beta 5a.	0.749
LOC101062666	LOC101077498	ENSTRUP00000069583	ENSTRUP00000019298	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide binding protein (G protein), beta 5b.	0.749
LOC101062666	LOC115250008	ENSTRUP00000069583	ENSTRUP00000057470	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.871
LOC101062666	gnb1	ENSTRUP00000069583	ENSTRUP00000001674	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide binding protein (G protein), beta polypeptide 1a.	0.876
LOC101062666	gnb2	ENSTRUP00000069583	ENSTRUP00000076510	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide binding protein (G protein), beta polypeptide 2.	0.876
LOC101062666	gnb4	ENSTRUP00000069583	ENSTRUP00000055099	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide binding protein (G protein), beta polypeptide 4b.	0.876
LOC101062666	gng2	ENSTRUP00000069583	ENSTRUP00000076429	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.735
LOC101062666	htr1d	ENSTRUP00000069583	ENSTRUP00000021543	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	5-hydroxytryptamine receptor 1D; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Regulates the release of 5-hydroxytryptamine in the brain, and thereby affects neural activity. May also play a role in regulating the release of other neurotransmitters. May play a role in vasoconstriction (By similarity).	0.723
LOC101069051	GNG4	ENSTRUP00000025511	ENSTRUP00000063062	Guanine nucleotide binding protein (G protein), beta polypeptide 3a.	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4.	0.624

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