Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
zfand1Zinc finger, AN1-type domain 1. (269 aa)    
Predicted Functional Partners:
nsfl1c
NSFL1 (p97) cofactor (p47).
    
 
 0.804
psmd1
26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.
   
 
 0.757
psmd6
Proteasome 26S subunit, non-ATPase 6.
   
 
 0.734
nploc4
NPL4 homolog, ubiquitin recognition factor.
    
 
 0.720
FAAP100
Uncharacterized protein.
    
 
 0.720
LOC101062380
Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family.
   
   0.704
psmc4
Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family.
   
   0.703
psmd7
Proteasome 26S subunit, non-ATPase 7.
   
 
 0.701
vcp
Valosin containing protein; Belongs to the AAA ATPase family.
   
 
 0.700
spata5l1
Spermatogenesis associated 5-like 1.
   
 
 0.691
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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