CLSPN protein (Takifugu rubripes) - STRING interaction network

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[Homology]

Score

CLSPN

Claspin. (1321 aa)

Predicted Functional Partners:

chek1

0.997

topbp1

0.990

cdc45

0.986

rpa3

0.980

timeless

0.978

cdc7

0.972

primpol

0.967

atr

0.959

tipin

0.959

RPA1

0.949

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLSPN	RPA1	ENSTRUP00000021610	ENSTRUP00000000950	Claspin.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.949
CLSPN	atr	ENSTRUP00000021610	ENSTRUP00000035419	Claspin.	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.959
CLSPN	cdc45	ENSTRUP00000021610	ENSTRUP00000042171	Claspin.	CDC45 cell division cycle 45 homolog (S. cerevisiae).	0.986
CLSPN	cdc7	ENSTRUP00000021610	ENSTRUP00000007900	Claspin.	Cell division cycle 7 homolog (S. cerevisiae).	0.972
CLSPN	chek1	ENSTRUP00000021610	ENSTRUP00000043876	Claspin.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.997
CLSPN	primpol	ENSTRUP00000021610	ENSTRUP00000045039	Claspin.	Primase and polymerase (DNA-directed).	0.967
CLSPN	rpa3	ENSTRUP00000021610	ENSTRUP00000056690	Claspin.	Replication protein A3.	0.980
CLSPN	timeless	ENSTRUP00000021610	ENSTRUP00000047331	Claspin.	Timeless circadian clock.	0.978
CLSPN	tipin	ENSTRUP00000021610	ENSTRUP00000050212	Claspin.	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	0.959
CLSPN	topbp1	ENSTRUP00000021610	ENSTRUP00000016012	Claspin.	DNA topoisomerase II binding protein 1.	0.990
RPA1	CLSPN	ENSTRUP00000000950	ENSTRUP00000021610	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	Claspin.	0.949
RPA1	atr	ENSTRUP00000000950	ENSTRUP00000035419	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.927
RPA1	cdc45	ENSTRUP00000000950	ENSTRUP00000042171	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	CDC45 cell division cycle 45 homolog (S. cerevisiae).	0.872
RPA1	cdc7	ENSTRUP00000000950	ENSTRUP00000007900	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	Cell division cycle 7 homolog (S. cerevisiae).	0.635
RPA1	chek1	ENSTRUP00000000950	ENSTRUP00000043876	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.555
RPA1	primpol	ENSTRUP00000000950	ENSTRUP00000045039	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	Primase and polymerase (DNA-directed).	0.892
RPA1	rpa3	ENSTRUP00000000950	ENSTRUP00000056690	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	Replication protein A3.	0.998
RPA1	timeless	ENSTRUP00000000950	ENSTRUP00000047331	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	Timeless circadian clock.	0.914
RPA1	tipin	ENSTRUP00000000950	ENSTRUP00000050212	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.	0.919
RPA1	topbp1	ENSTRUP00000000950	ENSTRUP00000016012	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	DNA topoisomerase II binding protein 1.	0.782