Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sav1Salvador family WW domain containing protein 1. (403 aa)    
Predicted Functional Partners:
lats1
Large tumor suppressor kinase 1.
    
 0.989
lats2
Large tumor suppressor kinase 2.
    
 0.973
LOC101061984
Protein kinase domain-containing protein.
    
 0.968
LOC101073635
MOB kinase activator 1A.
    
 0.968
stk3
Serine/threonine kinase 3 (STE20 homolog, yeast).
    
 0.968
LOC101066108
MOB kinase activator 1Bb.
     
 0.965
LOC101079837
Angiomotin.
    
 0.942
yap1
Yes-associated protein 1.
    
 0.926
RASSF1
Ras association domain family member 1.
    
 
 0.888
H2UG80_TAKRU
Ras association domain family member 1.
    
 
 0.888
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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