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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rfx2Regulatory factor X, 2 (influences HLA class II expression). (735 aa)    
Predicted Functional Partners:
atr
ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.
    
 
 0.791
chek2
Checkpoint kinase 2.
   
 
 0.623
LOC101073098
Fork-head domain-containing protein.
    
 
 0.538
LOC101067147
Forkhead box J1b.
    
 
 0.538
mcidas
Multicilin.
      
 0.528
rfxap
Regulatory factor X-associated protein.
    
 
 0.505
btaf1
BTAF1 RNA polymerase II, B-TFIID transcription factor-associated.
    
   0.479
rfxank
Regulatory factor X-associated ankyrin-containing protein.
   
 
 0.441
ENSTRUP00000036826
annotation not available
    
 
 0.402
FOXJ3
Forkhead box J3.
    
 
 0.402
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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