Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
phlda2Pleckstrin homology-like domain, family A, member 2. (138 aa)    
Predicted Functional Partners:
slc22a18
Solute carrier family 22 member 18.
      
 0.724
pcdh12
Protocadherin 12.
      
 0.649
LOC101066578
Nucleosome assembly protein 1-like 4a; Belongs to the nucleosome assembly protein (NAP) family.
      
 0.617
LOC101070528
Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family.
      
 0.525
LOC101062402
Uncharacterized protein; Belongs to the potassium channel family.
      
 0.525
MEST
Mesoderm specific transcript.
      
 0.517
LOC101066348
Oxysterol-binding protein; Belongs to the OSBP family.
      
 0.494
OSBPL8
Oxysterol-binding protein; Belongs to the OSBP family.
      
 0.494
igf2
Insulin-like growth factor 2b.
      
 0.464
igf2r
Insulin-like growth factor 2 receptor.
      
 0.445
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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