Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mdh1Malate dehydrogenase. (378 aa)    
Predicted Functional Partners:
cs
Citrate synthase; Belongs to the citrate synthase family.
  
 0.989
fh
Fumarate hydratase.
  
 0.985
got2
Aspartate aminotransferase.
   
 0.981
got1
Aspartate aminotransferase.
   
 0.975
PC
Pyruvate carboxylase.
  
 0.968
me1
Malic enzyme.
  
 0.957
LOC101069651
ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
  
 0.957
me3
Malic enzyme.
  
 0.957
ACLY
ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
  
 0.957
LOC101071000
Phosphoenolpyruvate carboxykinase 1 (soluble).
  
 
 0.948
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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