Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
msgn1Mesogenin 1. (144 aa)    
Predicted Functional Partners:
LOC101070955
T-box transcription factor 6.
   
 0.867
LOC101077064
T-box transcription factor 16.
   
 0.840
LOC105417312
BHLH domain-containing protein.
   
 0.710
H2TKA6_TAKRU
T-box transcription factor 2a.
   
 0.642
LOC101067579
Inhibitor of DNA binding 1, HLH protein.
    
 0.641
ppp1r14b
Protein phosphatase 1, regulatory (inhibitor) subunit 14Bb.
      
 0.627
apip
Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis.
      
 0.627
id2
Inhibitor of DNA binding 2a.
    
 0.627
smc6
Structural maintenance of chromosomes protein 6; Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components (By similarity).
      
 0.609
LOC101071673
T-box transcription factor Ta.
   
 0.605
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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