Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MAP4K1Mitogen-activated protein kinase kinase kinase kinase 1; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (854 aa)    
Predicted Functional Partners:
ENSTRUP00000053105
Lymphocyte cytosolic protein 2a.
    
 
 0.604
LOC101061287
Ras-related GTP binding A.
    
 
 0.522
grb2
Growth factor receptor-bound protein 2b.
   
 
 0.483
LOC101061204
Uncharacterized protein.
   
 
 0.483
ENSTRUP00000018134
GRB2 related adaptor protein 2a.
   
 
 0.482
LOC101063794
GRB2 related adaptor protein 2a.
   
 
 0.482
crkl
V-crk avian sarcoma virus CT10 oncogene homolog-like.
    
 
 0.409
LOC101065989
CRK proto-oncogene, adaptor protein.
    
 
 0.409
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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