close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cxcr4C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (379 aa)    
Predicted Functional Partners:
cxcl12
Chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1); Belongs to the intercrine alpha (chemokine CxC) family.
   
 0.991
LOC101065739
Chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1).
   
 0.978
LOC101071876
Guanine nucleotide binding protein (G protein), alpha 13b.
    
 0.925
gna12
G protein subunit alpha 12.
    
 0.925
LOC101065558
Uncharacterized protein.
    
 0.925
ackr3
Atypical chemokine receptor 3a; Belongs to the G-protein coupled receptor 1 family.
    
0.862
LOC101076921
Arrestin, beta 2a.
   
 0.764
LOC101071585
Arrestin_C domain-containing protein.
   
 0.764
LOC101066066
Guanine nucleotide-binding protein subunit alpha-14.
   
 0.735
LOC101066291
Uncharacterized protein.
   
 0.735
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: medium (52%) [HD]