Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
cxcr4C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (379 aa)    
Predicted Functional Partners:
cxcl12
Chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1); Belongs to the intercrine alpha (chemokine CxC) family.
    
 0.996
LOC101065739
Chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1).
    
 0.993
LOC101071876
Guanine nucleotide binding protein (G protein), alpha 13b.
    
 0.918
gna12
G protein subunit alpha 12.
    
 0.918
LOC101065558
Uncharacterized protein.
    
 0.918
ackr3
Atypical chemokine receptor 3a; Belongs to the G-protein coupled receptor 1 family.
    
 0.915
LOC101076921
Arrestin, beta 2a.
    
 0.856
LOC101071585
Arrestin_C domain-containing protein.
    
 0.856
H2RJL7_TAKRU
Uncharacterized protein.
    
 0.856
LOC101061475
E3 ubiquitin-protein ligase.
    
 
 0.766
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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