STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
casp6Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. (303 aa)    
Predicted Functional Partners:
casp8
Uncharacterized protein; Belongs to the peptidase C14A family.
   
0.985
LOC101061322
Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
   
0.983
casp9
Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
    
0.982
LOC101077373
Lamin A; Belongs to the intermediate filament family.
    
 0.966
LOC101064143
Lamin L3; Belongs to the intermediate filament family.
    
 0.965
lmnb1
Lamin B1; Belongs to the intermediate filament family.
    
 0.965
lmnb2
Lamin B2; Belongs to the intermediate filament family.
    
 0.965
LMNA
Lamin A/C; Belongs to the intermediate filament family.
    
 0.965
LOC101075191
Uncharacterized protein; Belongs to the peptidase C14A family.
   
0.935
LOC101069102
Actin, cytoplasmic 3, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.
    
 0.917
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.