Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
bccipProtein BCCIP homolog; Belongs to the BCP1 family. (313 aa)    
Predicted Functional Partners:
rpl23
Ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family.
   
 
 0.954
eif6
Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.
   
 
 0.953
ebna1bp2
EBNA1 binding protein 2.
   
  
 0.926
LOC105417819
Cyclin-dependent kinase inhibitor 1A.
    
 
 0.878
rpf2
Ribosome production factor 2 homolog.
   
  
 0.876
LOC101079595
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 
 0.857
brix1
Brix domain containing 2.
   
    0.843
nifk
Nucleolar protein interacting with the FHA domain of MKI67.
   
    0.839
imp4
IMP U3 small nucleolar ribonucleoprotein 4.
   
    0.834
lyar
Ly1 antibody reactive homolog (mouse).
   
  
 0.820
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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