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Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
il12bInterleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (359 aa)    
Predicted Functional Partners:
LOC101072499
Uncharacterized protein.
   
 0.995
LOC101077588
Uncharacterized protein.
  
  
 
0.917
LOC101066952
Interleukin 12B, b.
  
  
 
0.911
LOC101061955
Interleukin-12 subunit alpha; Belongs to the IL-6 superfamily.
     
  0.900
il12a
Interleukin-12 subunit alpha; Belongs to the IL-6 superfamily.
     
  0.900
ENSTRUP00000051078
Uncharacterized protein.
   
 0.837
LOC101073316
Tyrosine-protein kinase.
    
 0.774
stat3
Signal transducer and activator of transcription.
   
 0.766
il10
Interleukin 10.
     
 0.748
il6st
Uncharacterized protein.
   
 0.739
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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