STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101063905Cyclin D3; Belongs to the cyclin family. (300 aa)    
Predicted Functional Partners:
cdk6
Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily.
   
 0.979
cdk4
Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.
   
 0.976
rbl1
Retinoblastoma-like 1 (p107).
    
 0.964
LOC101070901
Retinoblastoma-like 2 (p130).
    
 0.964
LOC115246431
Retinoblastoma 1.
    
 0.964
LOC105417819
Cyclin-dependent kinase inhibitor 1A.
   
 0.959
ENSTRUP00000069966
Cyclin-dependent kinase 6-like isoform X2.
   
 0.953
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
    
 0.940
gsk3b
Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily.
    
 0.925
cdkn2d
Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4).
    
 0.919
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.