Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC101063905Cyclin D3; Belongs to the cyclin family. (300 aa)    
Predicted Functional Partners:
cdk6
Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily.
   
 0.977
cdk4
Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.
   
 0.970
rbl1
Retinoblastoma-like 1 (p107).
    
 0.962
LOC101070901
Retinoblastoma-like 2 (p130).
    
 0.962
LOC115246431
Retinoblastoma 1.
    
 0.962
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
    
 0.961
LOC105417819
Cyclin-dependent kinase inhibitor 1A.
   
 0.958
LOC101079162
Cyclin-dependent kinase inhibitor 1D.
   
 0.954
ENSTRUP00000069966
Cyclin-dependent kinase 6-like isoform X2.
   
 0.945
gsk3b
Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily.
    
 0.931
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.