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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
wdr53WD repeat domain 53. (382 aa)    
Predicted Functional Partners:
prpf6
PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae).
   
 0.993
snrnp200
Small nuclear ribonucleoprotein 200 (U5).
   
 0.991
prpf31
PRP31 pre-mRNA processing factor 31 homolog (yeast).
   
 0.991
SART1
Squamous cell carcinoma antigen recognised by cytotoxic T lymphocytes.
    
 0.988
lsm8
U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.
   
 0.986
lsm7
LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated.
    
 0.984
prpf8
Pre-mRNA processing factor 8.
   
 0.982
eftud2
Elongation factor Tu GTP binding domain containing 2.
   
 0.974
prpf3
PRP3 pre-mRNA processing factor 3 homolog (yeast).
   
 0.974
ENSTRUP00000079148
U4/U6 small nuclear ribonucleoprotein Prp3 isoform X1.
   
 0.974
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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