Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mcfd2Multiple coagulation factor deficiency 2. (194 aa)    
Predicted Functional Partners:
lman1
Lectin, mannose-binding, 1.
   
 0.999
f8
Uncharacterized protein; Belongs to the multicopper oxidase family.
     
 0.761
LOC445945
Coagulation factor V; Belongs to the multicopper oxidase family.
     
 0.761
wipf2
WAS/WASL interacting protein family, member 2a.
      
 0.753
mrpl45
Mitochondrial ribosomal protein L45.
      
 0.751
H2TRS2_TAKRU
Dexi homolog (mouse).
      
 0.734
H2V7Q0_TAKRU
SEC24 homolog C, COPII coat complex component.
     
 0.710
ctsc
Cathepsin C; Belongs to the peptidase C1 family.
     
 0.678
ttc7a
Tetratricopeptide repeat domain 7A.
      
 0.656
lman2
Lectin, mannose-binding 2.
     
 0.645
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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