Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
smg8SMG8 nonsense mediated mRNA decay factor. (938 aa)    
Predicted Functional Partners:
smg9
SMG9 nonsense mediated mRNA decay factor.
    
 0.999
smg1
SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family.
   
 0.999
smg5
SMG5 nonsense mediated mRNA decay factor.
     
 0.963
smg6
SMG6 nonsense mediated mRNA decay factor.
     
 0.954
rbm8a
RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
    
 
 0.928
dcp1a
Decapping mRNA 1A.
   
 
 0.862
LOC101068749
Proline-rich nuclear receptor coactivator 2.
     
 0.853
mtor
Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.
   
 0.837
prkdc
Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.
   
 0.835
dhx34
DEAH (Asp-Glu-Ala-His) box polypeptide 34.
   
  
 0.810
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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