Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC101065015Src homology 2 domain containing transforming protein D, b. (393 aa)    
Predicted Functional Partners:
mpv17
Mitochondrial inner membrane protein MPV17; Belongs to the peroxisomal membrane protein PXMP2/4 family.
      
 0.631
LOC101080135
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.610
crkl
V-crk avian sarcoma virus CT10 oncogene homolog-like.
    
 0.551
LOC101065989
CRK proto-oncogene, adaptor protein.
    
 0.551
LOC101069631
Melanocyte inducing transcription factor a.
      
 0.518
pck2
Phosphoenolpyruvate carboxykinase 2 (mitochondrial).
      
 0.518
flt4
Fms-related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    
  0.480
LOC101071220
Kinase insert domain receptor like; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    
  0.480
flt1
Uncharacterized protein.
    
  0.480
kdr
Kinase insert domain receptor (a type III receptor tyrosine kinase); Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    
  0.480
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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