Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tpx2TPX2 microtubule nucleation factor. (672 aa)    
Predicted Functional Partners:
dlgap5
Discs, large (Drosophila) homolog-associated protein 5.
   
  
 0.974
aurka
Aurora kinase A; Belongs to the protein kinase superfamily.
   
 0.968
LOC101076892
Aurora kinase B; Belongs to the protein kinase superfamily.
   
 0.968
kif11
Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
 0.963
ube2c
Uncharacterized protein.
   
 
 0.963
LOC101062741
Baculoviral IAP repeat containing 5a.
   
 0.956
bub1
BUB1 mitotic checkpoint serine/threonine kinase.
   
  
 0.951
LOC101075878
Marker of proliferation Ki-67.
   
 
 0.940
aspm
ASH domain-containing protein.
   
  
 0.937
kif4a
Kinesin family member 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
  
 0.935
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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