Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ric8bRIC8 guanine nucleotide exchange factor B. (541 aa)    
Predicted Functional Partners:
LOC101065996
GNAS complex locus.
   
 
 0.819
gnas
Uncharacterized protein.
   
 
 0.819
ncs1
Neuronal calcium sensor 1a.
    
 
 0.713
tceanc2
Uncharacterized protein.
      
 0.700
lrrc42
Leucine rich repeat containing 42.
      
 0.699
exd2
Exonuclease 3'-5' domain containing 2.
      
 0.697
dcaf5
Ddb1 and cul4 associated factor 5.
      
 0.696
polr3b
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
      
 0.639
nap1l1
Nucleosome assembly protein 1-like 1; Belongs to the nucleosome assembly protein (NAP) family.
    
   0.639
reep1-2
Receptor expression-enhancing protein.
      
 0.638
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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