Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1232 aa)    
Predicted Functional Partners:
LOC101066291
Uncharacterized protein.
    
 0.982
LOC101063826
Guanine nucleotide binding protein (G protein), alpha 11a (Gq class).
    
 0.977
LOC101066066
Guanine nucleotide-binding protein subunit alpha-14.
    
 0.976
PLCB1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
  
  
0.967
LOC101069591
PH_14 domain-containing protein.
  
  
0.964
LOC101076768
Uncharacterized protein.
    
 0.955
LOC101077978
Guanine nucleotide binding protein (G protein), alpha 14.
    
 0.955
LOC101070011
Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.
    
 0.955
itpr2
Inositol 1,4,5-trisphosphate receptor, type 2.
    
 0.952
LOC101074739
Inositol 1,4,5-trisphosphate receptor, type 1a.
    
 0.952
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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