Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
txndc16Thioredoxin domain containing 16. (810 aa)    
Predicted Functional Partners:
ankrd54
FAD-dependent oxidoreductase domain containing 2.
    
 
 0.937
hspa5
Heat shock protein 5; Belongs to the heat shock protein 70 family.
   
 0.732
styx
Serine/threonine/tyrosine interacting protein.
     
 0.724
ENSTRUP00000063924
Kelch-like protein 25/37 (ectoderm-neural cortex protein).
    
 
 0.720
H2S6A2_TAKRU
PDZ domain-containing protein.
      
 0.713
gpr137c
G protein-coupled receptor 137c.
      
 0.709
Khk
Ketohexokinase isoform X1.
      
 0.702
rtraf
RNA transcription, translation and transport factor.
      
 0.672
eef1g
Eukaryotic translation elongation factor 1 gamma.
   
 
 0.639
ddhd1
DDHD domain containing 1a.
      
 0.638
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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