Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nsdhlNAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family. (345 aa)    
Predicted Functional Partners:
msmo1
Methylsterol monooxygenase 1; Belongs to the sterol desaturase family.
   
 0.994
hsd17b7
Hydroxysteroid (17-beta) dehydrogenase 7.
   
 0.993
lss
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
 
 
 0.935
sc5d
Sterol-C5-desaturase; Belongs to the sterol desaturase family.
   
 0.926
fdft1
Farnesyl-diphosphate farnesyltransferase 1.
  
 
 0.918
hmgcs1
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
   
  
 0.911
LOC101071896
7-dehydrocholesterol reductase.
   
 
 0.889
LOC101077849
Cholesterol 25-hydroxylase like 2; Belongs to the sterol desaturase family.
   
 0.877
mvd
Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.
  
 
 0.873
fau
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 0.856
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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