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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
shc2SHC (Src homology 2 domain containing) transforming protein 2. (718 aa)    
Predicted Functional Partners:
LOC101074842
Receptor protein-tyrosine kinase.
    
 0.962
grb2
Growth factor receptor-bound protein 2b.
   
0.962
LOC101061551
Uncharacterized protein.
    
 0.962
erbb3
Protein kinase domain-containing protein.
    
 0.962
LOC101061204
Uncharacterized protein.
   
 0.962
egfr
Receptor protein-tyrosine kinase.
    
 0.962
LOC101074687
Receptor protein-tyrosine kinase.
    
 0.962
erbb4
Receptor protein-tyrosine kinase.
    
 0.962
LOC101074083
Tyrosine-protein kinase receptor.
    
 0.958
kdr
Kinase insert domain receptor (a type III receptor tyrosine kinase); Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
 0.950
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.