STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dstykDual serine/threonine and tyrosine protein kinase; May act as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. May induce both caspase-dependent apoptosis and caspase-independent cell death. May play a role in the embryonic development. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (921 aa)    
Predicted Functional Partners:
bysl
Bystin-like.
   
 
 0.632
mib2
Mindbomb E3 ubiquitin protein ligase 2.
   
 0.616
med20
Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
     
 0.615
LOC101074738
Retinoblastoma binding protein 5.
 
  
 
 0.586
spg11
Spatacsin_C domain-containing protein.
      
 0.566
qser1
Glutamine and serine rich 1.
      
 0.561
nufip2
Uncharacterized protein.
    
 
 0.561
cd247
Uncharacterized protein.
   
 0.548
tradd
Tnfrsf1a-associated via death domain.
   
 0.538
birc6
Baculoviral IAP repeat containing 6.
   
 0.524
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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