Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FAT4FAT atypical cadherin 4. (4962 aa)    
Predicted Functional Partners:
fjx1
Four-jointed box kinase 1.
   
 
 0.727
ctnnb1
Catenin (cadherin-associated protein), beta 1.
    
 0.720
AXIN2
Axin 2.
    
 
 0.696
yap1
Yes-associated protein 1.
    
 
 0.656
irx3
Iroquois homeobox 3a.
      
 0.654
ctnna1
Catenin (cadherin-associated protein), alpha 1.
   
 0.613
ctnna2
Catenin (cadherin-associated protein), alpha 2.
   
 0.613
H2SRJ8_TAKRU
Dachsous cadherin-related 1b.
   
 
 0.594
dchs2
Si:dkey-30k22.7.
   
 
 0.594
LOC101062627
Dachsous cadherin-related 1a.
   
 
 0.594
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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