Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
vps28Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (228 aa)    
Predicted Functional Partners:
vps25
Vacuolar protein sorting 25 homolog.
   
 0.998
vps37b
Zgc:114173.
   
 0.998
vps37a
VPS37A subunit of ESCRT-I.
   
 0.998
ENSTRUP00000034070
annotation not available
   
 0.996
vps36
Vacuolar protein sorting 36 homolog.
    
 0.996
mvb12b
Multivesicular body subunit 12Ba.
   
 0.995
LOC101068384
Tumor susceptibility gene 101 protein-like.
   
 0.995
LOC101079670
Tumor susceptibility 101a.
   
 0.995
snf8
Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.
   
 0.994
LOC101064065
VPS37C subunit of ESCRT-I.
   
 0.985
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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