Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lrp3Low density lipoprotein receptor-related protein 3. (817 aa)    
Predicted Functional Partners:
aplp1
Amyloid beta (A4) precursor-like protein 1.
    
 0.716
prkn
Ubiquitin-like domain-containing protein.
      
 0.642
fkrp
Fukutin related protein.
     
 0.629
LOC101077791
Uncharacterized protein.
    
 0.587
gdpd2
Glycerophosphodiester phosphodiesterase domain containing 2.
      
 0.560
itsn1
Intersectin 1 (SH3 domain protein).
    
 0.524
LOC101074738
Retinoblastoma binding protein 5.
      
 0.520
manf
Mesencephalic astrocyte-derived neurotrophic factor.
      
 0.510
srd5a3
Steroid 5 alpha-reductase 3.
      
 0.508
vwa5b2
VIT domain-containing protein.
      
 0.497
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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