Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
KCNN2Potassium calcium-activated channel subfamily N member 2. (542 aa)    
Predicted Functional Partners:
LOC101061965
Gamma-aminobutyric acid (GABA) A receptor, alpha 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
   
  
 0.602
ENSTRUP00000008077
Calmodulin 1b.
    
 
 0.588
calm2
Calmodulin 2a (phosphorylase kinase, delta); Belongs to the calmodulin family.
    
 
 0.588
calm2-2
Calmodulin 3.
    
 
 0.588
LOC101064505
Uncharacterized protein; Belongs to the calmodulin family.
    
 
 0.588
H2V4V2_TAKRU
Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.
      
 0.561
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
      
 0.549
thrb
Thyroid hormone receptor beta.
      
 0.542
KCNMA1
Potassium calcium-activated channel subfamily M alpha 1.
   
  
 0.522
dio2
Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine).
      
 0.509
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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