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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdgfrlPlatelet-derived growth factor receptor-like. (370 aa)    
Predicted Functional Partners:
LOC101070662
PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.
    
 0.727
LOC101070662-2
PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.
    
 0.727
vegfc
Vascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family.
    
 0.664
nrp1
Neuropilin; Belongs to the neuropilin family.
    
 0.653
rasa1
RAS p21 protein activator (GTPase activating protein) 1a.
    
 0.633
LOC101063539
Platelet-derived growth factor alpha polypeptide a; Belongs to the PDGF/VEGF growth factor family.
    
 0.630
LOC101075732
Uncharacterized protein LOC101075732 isoform X1.
   
 0.625
pdgfb
Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family.
   
 0.625
grb2
Growth factor receptor-bound protein 2b.
   
 0.619
LOC101061204
Uncharacterized protein.
   
 0.619
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.