STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
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[Homology]
Score
LOC101068124Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. Belongs to the ubiA prenyltransferase family. (470 aa)    
Predicted Functional Partners:
LOC101068591
Cytochrome c oxidase assembly homolog 15 (yeast).
  
 0.999
LOC101061825
Cytochrome c heme lyase; Links covalently the heme group to the apoprotein of cytochrome c.
   
 
 0.954
Fech
Protoporphyrin/coproporphyrin ferrochelatase.
     
 0.954
LOC101071475
Cytochrome c oxidase assembly homolog 11 (yeast).
  
 
 0.947
LOC101074563
Surfeit locus protein 1; May play a role in mitochondrial respiratory chain complex IV assembly. Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family.
  
 
 0.924
hmox2
Heme oxygenase 2b.
     
 0.906
hmox1
Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed.
     
 0.906
clcc1
Uncharacterized protein.
  
 
 0.826
abcb10
ATP-binding cassette, sub-family B (MDR/TAP), member 10.
 
    
 0.745
dhtkd1
Dehydrogenase E1 and transketolase domain containing 1.
   
  
 0.742
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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