Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
Experiments
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[Homology]
Score
LOC101062799Retinal homeobox gene 2. (326 aa)    
Predicted Functional Partners:
cib3
Calcium and integrin binding family member 3.
    
 
 0.575
wac
WW domain containing adaptor with coiled-coil a.
      
 0.548
LOC101066059
Solute carrier family 2 member 15b; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
      
 0.540
LOC101074968
AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
    
 
 0.535
LOC101063828
Adaptor related protein complex 1 subunit mu 3; Belongs to the adaptor complexes medium subunit family.
    
 
 0.535
LOC101061845
NME/NM23 family member 8; Belongs to the NDK family.
    
   0.529
LOC101073512
Paired box 2a.
    
 0.495
LOC101068913
Growth differentiation factor 6a.
   
 
 0.468
cib2
Calcium and integrin binding family member 2.
    
 
 0.468
LOC101076766
Opioid receptor, kappa 1; Belongs to the G-protein coupled receptor 1 family.
   
 
 0.444
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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