| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| H2UF66_TAKRU | LOC101063139 | ENSTRUP00000035585 | ENSTRUP00000076139 | Cytochrome P450, family 1, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] | 0.422 |
| H2UF66_TAKRU | LOC101065426 | ENSTRUP00000035585 | ENSTRUP00000024022 | Cytochrome P450, family 1, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. | Cytochrome P450, family 20, subfamily A, polypeptide 1. | 0.593 |
| H2UF66_TAKRU | aasdh | ENSTRUP00000035585 | ENSTRUP00000040155 | Cytochrome P450, family 1, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. | Aminoadipate-semialdehyde dehydrogenase. | 0.666 |
| H2UF66_TAKRU | lss | ENSTRUP00000035585 | ENSTRUP00000033247 | Cytochrome P450, family 1, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. | 0.433 |
| H2UF66_TAKRU | pfcyp19a | ENSTRUP00000035585 | ENSTRUP00000070170 | Cytochrome P450, family 1, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.530 |
| LOC101063139 | H2UF66_TAKRU | ENSTRUP00000076139 | ENSTRUP00000035585 | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] | Cytochrome P450, family 1, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. | 0.422 |
| LOC101063139 | LOC101065426 | ENSTRUP00000076139 | ENSTRUP00000024022 | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] | Cytochrome P450, family 20, subfamily A, polypeptide 1. | 0.666 |
| LOC101063139 | LOC101069556 | ENSTRUP00000076139 | ENSTRUP00000027981 | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] | Cytochrome P450, family 7, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. | 0.446 |
| LOC101063139 | LOC101073682 | ENSTRUP00000076139 | ENSTRUP00000040455 | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.483 |
| LOC101063139 | aasdh | ENSTRUP00000076139 | ENSTRUP00000040155 | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] | Aminoadipate-semialdehyde dehydrogenase. | 0.666 |
| LOC101063139 | lss | ENSTRUP00000076139 | ENSTRUP00000033247 | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. | 0.433 |
| LOC101065426 | H2UF66_TAKRU | ENSTRUP00000024022 | ENSTRUP00000035585 | Cytochrome P450, family 20, subfamily A, polypeptide 1. | Cytochrome P450, family 1, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. | 0.593 |
| LOC101065426 | LOC101063139 | ENSTRUP00000024022 | ENSTRUP00000076139 | Cytochrome P450, family 20, subfamily A, polypeptide 1. | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] | 0.666 |
| LOC101065426 | LOC101069556 | ENSTRUP00000024022 | ENSTRUP00000027981 | Cytochrome P450, family 20, subfamily A, polypeptide 1. | Cytochrome P450, family 7, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. | 0.650 |
| LOC101065426 | LOC101073682 | ENSTRUP00000024022 | ENSTRUP00000040455 | Cytochrome P450, family 20, subfamily A, polypeptide 1. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.687 |
| LOC101065426 | aasdh | ENSTRUP00000024022 | ENSTRUP00000040155 | Cytochrome P450, family 20, subfamily A, polypeptide 1. | Aminoadipate-semialdehyde dehydrogenase. | 0.719 |
| LOC101065426 | abi2 | ENSTRUP00000024022 | ENSTRUP00000063699 | Cytochrome P450, family 20, subfamily A, polypeptide 1. | Abl-interactor 2b. | 0.708 |
| LOC101065426 | lss | ENSTRUP00000024022 | ENSTRUP00000033247 | Cytochrome P450, family 20, subfamily A, polypeptide 1. | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. | 0.616 |
| LOC101065426 | nbeal1 | ENSTRUP00000024022 | ENSTRUP00000076346 | Cytochrome P450, family 20, subfamily A, polypeptide 1. | Neurobeachin-like 1. | 0.650 |
| LOC101065426 | pfcyp19a | ENSTRUP00000024022 | ENSTRUP00000070170 | Cytochrome P450, family 20, subfamily A, polypeptide 1. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.579 |