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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101065426Cytochrome P450, family 20, subfamily A, polypeptide 1. (463 aa)    
Predicted Functional Partners:
aasdh
Aminoadipate-semialdehyde dehydrogenase.
  
 0.719
abi2
Abl-interactor 2b.
 
    
 0.708
LOC101073682
Uncharacterized protein; Belongs to the cytochrome P450 family.
  
 0.687
LOC101063139
Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]
  
 
 
 0.666
LOC101069556
Cytochrome P450, family 7, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family.
  
 
 0.650
nbeal1
Neurobeachin-like 1.
 
      0.650
lss
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
  
 0.616
H2UF66_TAKRU
Cytochrome P450, family 1, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family.
  
 0.593
pfcyp19a
Uncharacterized protein; Belongs to the cytochrome P450 family.
  
   
 0.579
srd5a3
Steroid 5 alpha-reductase 3.
      
 0.566
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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