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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101074526Calreticulin. (425 aa)    
Predicted Functional Partners:
tapbp
TAP binding protein (tapasin), tandem duplicate 2.
    
 0.989
pdia3
Protein disulfide-isomerase.
   
 0.983
hsp90b1
Heat shock protein 90, beta (grp94), member 1.
   
 0.981
LOC101067334
Protein disulfide-isomerase.
   
 0.970
LOC101070568
Transporter associated with antigen processing, subunit type t, teleost specific.
   
 0.939
LOC101066072
Transporter associated with antigen processing, subunit type a.
   
 0.939
hspa5
Heat shock protein 5; Belongs to the heat shock protein 70 family.
   
 0.934
calr
Calreticulin.
  
  
0.915
pdia6
Protein disulfide isomerase family A, member 6; Belongs to the protein disulfide isomerase family.
   
 0.903
pdia4
Protein disulfide-isomerase A4; Belongs to the protein disulfide isomerase family.
   
 0.885
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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