Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC101074526Calreticulin. (425 aa)    
Predicted Functional Partners:
hsp90b1
Heat shock protein 90, beta (grp94), member 1.
   
 0.991
pdia3
Protein disulfide-isomerase.
   
 0.990
hspa5
Heat shock protein 5; Belongs to the heat shock protein 70 family.
   
 0.979
LOC101067334
Protein disulfide-isomerase.
   
 0.974
tapbp
TAP binding protein (tapasin), tandem duplicate 2.
    
 0.963
pdia6
Protein disulfide isomerase family A, member 6; Belongs to the protein disulfide isomerase family.
   
 0.943
LOC101079880
Uncharacterized protein.
    
 0.938
pdia4
Protein disulfide-isomerase A4; Belongs to the protein disulfide isomerase family.
   
 0.933
LOC105418295
C1q domain-containing protein.
     
 0.909
calr
Calreticulin.
  
  
 
0.901
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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