Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC101062014ADAM metallopeptidase domain 15. (913 aa)    
Predicted Functional Partners:
LOC101073075
Anion exchange protein.
      
 0.708
LOC101077006
Empty spiracles homeobox 1.
      
 0.516
sec23a
Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.
      
 0.512
sepsecs
LRRCT domain-containing protein.
     
 0.489
HYAL2
Hyaluronidase.
   
 
 0.465
HYAL2-2
Hyaluronidase.
   
 
 0.465
LOC101072113
Hyaluronidase.
   
 
 0.465
sh3pxd2b
SH3 and PX domains 2B.
    
 0.452
SH3PXD2A
SH3 and PX domains 2A.
    
 0.452
LOC101063901
SH3 and PX domains 2Aa.
    
 0.452
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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