Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
klf4Kruppel-like factor 4. (445 aa)    
Predicted Functional Partners:
LOC101074260
POU domain protein.
    
 0.602
lmo2
LIM domain only 2 (rhombotin-like 1).
   
 0.597
myb
V-myb avian myeloblastosis viral oncogene homolog.
   
 0.592
dr1
Down-regulator of transcription 1.
    
 
 0.542
LOC101075116
Lin-28 homolog A.
    
 0.483
myc
Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.
   
 
 0.461
slc26a6
Solute carrier family 26 member 6.
   
 
 0.451
cebpd
CCAAT/enhancer-binding protein.
   
 0.447
mysm1
Histone H2A deubiquitinase MYSM1.
    
  0.442
LOC101061845
NME/NM23 family member 8; Belongs to the NDK family.
    
 0.417
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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