Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
afap1Actin filament associated protein 1. (824 aa)    
Predicted Functional Partners:
txnrd2
Thioredoxin reductase 2, tandem duplicate 1.
      
 0.627
gmds
GDP-mannose 4,6-dehydratase.
      
 0.601
tgfbr3
Transforming growth factor, beta receptor III.
     
 0.562
tmco1
Calcium load-activated calcium channel; Calcium-selective channel required to prevent calcium stores from overfilling.
      
 0.553
lrp12
Low density lipoprotein receptor-related protein 12.
      
 0.519
LOC101076389
F-BAR domain-containing protein.
     
 0.498
gas7
Growth arrest-specific 7a.
     
 0.498
fndc3b
Fibronectin type III domain containing 3Ba.
      
 0.449
gemin4
Gem (nuclear organelle) associated protein 4.
      
 0.442
vps53
VPS53 subunit of GARP complex.
      
 0.441
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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