Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sil1SIL1 nucleotide exchange factor. (460 aa)    
Predicted Functional Partners:
hyou1
Hypoxia up-regulated 1.
   
 0.993
hspa5
Heat shock protein 5; Belongs to the heat shock protein 70 family.
   
 
 0.985
fau
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 0.935
rpl23a
Ribosomal protein L23a; Belongs to the universal ribosomal protein uL23 family.
  
 0.928
rpl13a
Ribosomal protein L13a; Belongs to the universal ribosomal protein uL13 family.
  
 0.926
rpl11
Ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family.
  
 0.925
rpl9
Ribosomal protein L9.
  
 0.922
mrpl12
Mitochondrial ribosomal protein L12.
  
 0.910
mrpl17
Mitochondrial ribosomal protein L17.
  
 0.910
rpl23
Ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family.
  
 0.909
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: medium (44%) [HD]