Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
wee1Wee1-like protein kinase. (645 aa)    
Predicted Functional Partners:
LOC101064374
Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.983
chek1
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.927
ccnb1
Cyclin B1; Belongs to the cyclin family.
   
 0.926
plk3
Serine/threonine-protein kinase PLK.
   
 0.920
cdc25b
Cell division cycle 25B.
   
 0.916
LOC101071662
Wee1-like protein kinase.
  
  
 
0.903
ccna1
Cyclin-A1 isoform X1.
   
 0.882
ccna2
Cyclin A2; Belongs to the cyclin family.
   
 0.863
plk4
Polo-like kinase 4 (Drosophila).
   
 0.847
cdk4
Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.
   
 0.817
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.