STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
spdl1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex; Belongs to the Spindly family. (568 aa)    
Predicted Functional Partners:
ska1
Spindle and kinetochore associated complex subunit 1.
   
 
  0.813
LOC101067654
SKA2 domain-containing protein.
     
  0.784
LOC101067654-2
SKA2 domain-containing protein.
     
  0.784
sgo1
Shugoshin_C domain-containing protein.
   
 
 0.719
plk3
Serine/threonine-protein kinase PLK.
   
 
  0.670
KIF18A
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
  0.668
ckap5
Cytoskeleton associated protein 5.
     
 0.659
LOC101066737
NDC80 kinetochore complex component.
   
 
 0.655
LOC115248170
Kinetochore protein NDC80 homolog.
   
 
 0.655
spc25
SPC25 component of NDC80 kinetochore complex.
   
 
 0.648
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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