STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spdl1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex; Belongs to the Spindly family. (568 aa)    
Predicted Functional Partners:
LOC101063487
Cell division cycle 20 homolog.
   
 
  0.617
ENSTRUP00000069968
annotation not available
   
 
  0.617
plk3
Serine/threonine-protein kinase PLK.
   
 
  0.612
plk4
Polo-like kinase 4 (Drosophila).
   
 
 0.607
ect2
Epithelial cell transforming 2.
  
    0.577
bub1b
BUB1 mitotic checkpoint serine/threonine kinase Bb.
   
 
 0.506
mad2l1
MAD2 mitotic arrest deficient-like 1 (yeast).
   
 
  0.495
LOC101076451
Fizzy/cell division cycle 20 related 1b.
   
 
  0.479
intu
Inturned planar cell polarity protein.
   
 
  0.479
FZR1
Fizzy/cell division cycle 20 related 1a.
   
 
  0.479
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.