STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101077240DNA (cytosine-5-)-methyltransferase 3 alpha b; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (985 aa)    
Predicted Functional Partners:
dnmt1
DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
    
 0.991
H2SKN2_TAKRU
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
  
0.982
ahcy
Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family.
     
 0.908
ahcyl1
Adenosylhomocysteinase-like 1; Belongs to the adenosylhomocysteinase family.
     
 0.902
AHCYL1
Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family.
     
 0.902
LOC101063003
DNA (cytosine-5-)-methyltransferase 3 alpha a; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
  
  
 
0.901
LOC101076394
AdoHcyase_NAD domain-containing protein.
     
  0.900
amd1
S-adenosylmethionine decarboxylase proenzyme.
     
  0.900
EZH1
Enhancer of zeste 1 polycomb repressive complex 2 subunit.
   
 0.777
HDAC2
Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
   
 0.700
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.