Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
casp8Uncharacterized protein; Belongs to the peptidase C14A family. (526 aa)    
Predicted Functional Partners:
tradd
Tnfrsf1a-associated via death domain.
   
 0.996
LOC101067067
DED domain-containing protein.
   
 0.996
cflar
Uncharacterized protein; Belongs to the peptidase C14A family.
   
0.995
ripk1
Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.
   
 0.994
LOC101076232
Uncharacterized protein.
   
 0.990
casp6
Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.
   
0.985
LOC101074300
Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family.
    
 0.968
ENSTRUP00000055918
Uncharacterized protein.
   
 0.965
LOC101074856
Uncharacterized protein; Belongs to the peptidase C14A family.
   
0.962
CASP3
Caspase 3; Belongs to the peptidase C14A family.
   
0.958
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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