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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101064982Proopiomelanocortin. (218 aa)    
Predicted Functional Partners:
mc4r
Melanocortin 4 receptor.
    
 0.998
mc1r
Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.
    
 0.996
mc5r
Melanocortin 5 receptor.
    
 0.987
pdyn
Prodynorphin.
     
 0.980
penk
Proenkephalin a.
     
 0.980
mc2r
G_PROTEIN_RECEP_F1_2 domain-containing protein.
    
 0.978
LOC101074721
Prepronociceptin a.
     
 0.963
LOC101075730
Opioid receptor, mu 1; Belongs to the G-protein coupled receptor 1 family.
    
 0.945
LOC101068751
Opioid receptor, delta 1b; Belongs to the G-protein coupled receptor 1 family.
    
 0.945
LOC101079075
Opioid receptor, delta 1a; Belongs to the G-protein coupled receptor 1 family.
    
 0.945
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.