Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC101064982Proopiomelanocortin. (218 aa)    
Predicted Functional Partners:
mc2r
G_PROTEIN_RECEP_F1_2 domain-containing protein.
    
 0.999
mc4r
Melanocortin 4 receptor.
    
 0.999
mc5r
Melanocortin 5 receptor.
    
 0.998
mc1r
Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.
    
 0.998
LOC101075730
Opioid receptor, mu 1; Belongs to the G-protein coupled receptor 1 family.
    
 0.988
penk
Proenkephalin a.
     
 0.988
pdyn
Prodynorphin.
     
 0.987
LOC101068751
Opioid receptor, delta 1b; Belongs to the G-protein coupled receptor 1 family.
    
 0.987
LOC101079075
Opioid receptor, delta 1a; Belongs to the G-protein coupled receptor 1 family.
    
 0.987
pcsk1
Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family.
    
 0.983
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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