Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
pdzrn3PDZ domain containing RING finger 3b. (1031 aa)    
Predicted Functional Partners:
mib2
Mindbomb E3 ubiquitin protein ligase 2.
    
 0.745
ripk4
Receptor-interacting serine-threonine kinase 4.
   
 0.683
birc6
Baculoviral IAP repeat containing 6.
   
 0.666
ecsit
ECSIT signalling integrator.
    
 0.582
ankrd22
Ankyrin repeat domain 22.
    
 0.579
rps27a
Ribosomal protein S27a.
    
 0.559
tradd
Tnfrsf1a-associated via death domain.
    
 0.548
tab2
TGF-beta activated kinase 1 (MAP3K7) binding protein 2.
    
 0.542
tab3
TGF-beta activated kinase 1 (MAP3K7) binding protein 3.
    
 0.542
MUSK
Muscle associated receptor tyrosine kinase.
    
 0.528
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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