node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Fancm | RPA1 | ENSTRUP00000024507 | ENSTRUP00000000950 | ERCC4 domain-containing protein. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.999 |
Fancm | ercc1 | ENSTRUP00000024507 | ENSTRUP00000033451 | ERCC4 domain-containing protein. | Excision repair cross-complementation group 1. | 0.999 |
Fancm | fancb | ENSTRUP00000024507 | ENSTRUP00000023252 | ERCC4 domain-containing protein. | FA complementation group B. | 0.999 |
Fancm | fancc | ENSTRUP00000024507 | ENSTRUP00000037064 | ERCC4 domain-containing protein. | FA complementation group C. | 0.999 |
Fancm | fance | ENSTRUP00000024507 | ENSTRUP00000041317 | ERCC4 domain-containing protein. | FA complementation group E. | 0.999 |
Fancm | fancf | ENSTRUP00000024507 | ENSTRUP00000030768 | ERCC4 domain-containing protein. | FA complementation group F. | 0.999 |
Fancm | nploc4 | ENSTRUP00000024507 | ENSTRUP00000011853 | ERCC4 domain-containing protein. | NPL4 homolog, ubiquitin recognition factor. | 0.999 |
Fancm | rmi2 | ENSTRUP00000024507 | ENSTRUP00000032434 | ERCC4 domain-containing protein. | RecQ mediated genome instability 2. | 0.999 |
Fancm | rpa1 | ENSTRUP00000024507 | ENSTRUP00000008475 | ERCC4 domain-containing protein. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.999 |
Fancm | rpl10a | ENSTRUP00000024507 | ENSTRUP00000041341 | ERCC4 domain-containing protein. | Ribosomal protein; Belongs to the universal ribosomal protein uL1 family. | 0.999 |
RPA1 | Fancm | ENSTRUP00000000950 | ENSTRUP00000024507 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | ERCC4 domain-containing protein. | 0.999 |
RPA1 | ercc1 | ENSTRUP00000000950 | ENSTRUP00000033451 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | Excision repair cross-complementation group 1. | 0.756 |
RPA1 | fancc | ENSTRUP00000000950 | ENSTRUP00000037064 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | FA complementation group C. | 0.543 |
RPA1 | fance | ENSTRUP00000000950 | ENSTRUP00000041317 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | FA complementation group E. | 0.427 |
RPA1 | rmi2 | ENSTRUP00000000950 | ENSTRUP00000032434 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | RecQ mediated genome instability 2. | 0.859 |
RPA1 | rpa1 | ENSTRUP00000000950 | ENSTRUP00000008475 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.901 |
RPA1 | rpl10a | ENSTRUP00000000950 | ENSTRUP00000041341 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | Ribosomal protein; Belongs to the universal ribosomal protein uL1 family. | 0.424 |
ercc1 | Fancm | ENSTRUP00000033451 | ENSTRUP00000024507 | Excision repair cross-complementation group 1. | ERCC4 domain-containing protein. | 0.999 |
ercc1 | RPA1 | ENSTRUP00000033451 | ENSTRUP00000000950 | Excision repair cross-complementation group 1. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.756 |
ercc1 | fancb | ENSTRUP00000033451 | ENSTRUP00000023252 | Excision repair cross-complementation group 1. | FA complementation group B. | 0.927 |