aptx protein (Takifugu rubripes) - STRING interaction network

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aptx

Aprataxin; DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined. Also able to hydrolyze adenosine 5'-monophosphoramidate (AMP- NH(2)) and diadenosine tetraphosphate (AppppA), b [...] (356 aa)

Predicted Functional Partners:

xrcc4

0.820

tonsl

0.782

emsy

0.768

LOC115250498

0.757

LOC101066034

0.757

tdp1

0.742

lig4

0.708

lig3

0.685

ogg1

0.660

parp2

0.656

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101066034	aptx	ENSTRUP00000070761	ENSTRUP00000024613	DNA repair protein XRCC1.	Aprataxin; DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined. Also able to hydrolyze adenosine 5'-monophosphoramidate (AMP- NH(2)) and diadenosine tetraphosphate (AppppA), b [...]	0.757
LOC101066034	lig3	ENSTRUP00000070761	ENSTRUP00000027352	DNA repair protein XRCC1.	DNA ligase.	0.972
LOC101066034	lig4	ENSTRUP00000070761	ENSTRUP00000025119	DNA repair protein XRCC1.	DNA ligase.	0.882
LOC101066034	ogg1	ENSTRUP00000070761	ENSTRUP00000007920	DNA repair protein XRCC1.	8-oxoguanine DNA glycosylase.	0.586
LOC101066034	parp2	ENSTRUP00000070761	ENSTRUP00000027488	DNA repair protein XRCC1.	Poly [ADP-ribose] polymerase.	0.748
LOC101066034	tdp1	ENSTRUP00000070761	ENSTRUP00000015997	DNA repair protein XRCC1.	Tyrosyl-DNA phosphodiesterase 1.	0.697
LOC101066034	xrcc4	ENSTRUP00000070761	ENSTRUP00000010998	DNA repair protein XRCC1.	Uncharacterized protein.	0.497
LOC115250498	aptx	ENSTRUP00000007413	ENSTRUP00000024613	X-ray repair complementing defective repair in Chinese hamster cells 1.	Aprataxin; DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined. Also able to hydrolyze adenosine 5'-monophosphoramidate (AMP- NH(2)) and diadenosine tetraphosphate (AppppA), b [...]	0.757
LOC115250498	lig3	ENSTRUP00000007413	ENSTRUP00000027352	X-ray repair complementing defective repair in Chinese hamster cells 1.	DNA ligase.	0.972
LOC115250498	lig4	ENSTRUP00000007413	ENSTRUP00000025119	X-ray repair complementing defective repair in Chinese hamster cells 1.	DNA ligase.	0.882
LOC115250498	ogg1	ENSTRUP00000007413	ENSTRUP00000007920	X-ray repair complementing defective repair in Chinese hamster cells 1.	8-oxoguanine DNA glycosylase.	0.586
LOC115250498	parp2	ENSTRUP00000007413	ENSTRUP00000027488	X-ray repair complementing defective repair in Chinese hamster cells 1.	Poly [ADP-ribose] polymerase.	0.748
LOC115250498	tdp1	ENSTRUP00000007413	ENSTRUP00000015997	X-ray repair complementing defective repair in Chinese hamster cells 1.	Tyrosyl-DNA phosphodiesterase 1.	0.697
LOC115250498	xrcc4	ENSTRUP00000007413	ENSTRUP00000010998	X-ray repair complementing defective repair in Chinese hamster cells 1.	Uncharacterized protein.	0.497
aptx	LOC101066034	ENSTRUP00000024613	ENSTRUP00000070761	Aprataxin; DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined. Also able to hydrolyze adenosine 5'-monophosphoramidate (AMP- NH(2)) and diadenosine tetraphosphate (AppppA), b [...]	DNA repair protein XRCC1.	0.757
aptx	LOC115250498	ENSTRUP00000024613	ENSTRUP00000007413	Aprataxin; DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined. Also able to hydrolyze adenosine 5'-monophosphoramidate (AMP- NH(2)) and diadenosine tetraphosphate (AppppA), b [...]	X-ray repair complementing defective repair in Chinese hamster cells 1.	0.757
aptx	emsy	ENSTRUP00000024613	ENSTRUP00000030357	Aprataxin; DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined. Also able to hydrolyze adenosine 5'-monophosphoramidate (AMP- NH(2)) and diadenosine tetraphosphate (AppppA), b [...]	EMSY transcriptional repressor, BRCA2 interacting.	0.768
aptx	lig3	ENSTRUP00000024613	ENSTRUP00000027352	Aprataxin; DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined. Also able to hydrolyze adenosine 5'-monophosphoramidate (AMP- NH(2)) and diadenosine tetraphosphate (AppppA), b [...]	DNA ligase.	0.685
aptx	lig4	ENSTRUP00000024613	ENSTRUP00000025119	Aprataxin; DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined. Also able to hydrolyze adenosine 5'-monophosphoramidate (AMP- NH(2)) and diadenosine tetraphosphate (AppppA), b [...]	DNA ligase.	0.708
aptx	ogg1	ENSTRUP00000024613	ENSTRUP00000007920	Aprataxin; DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined. Also able to hydrolyze adenosine 5'-monophosphoramidate (AMP- NH(2)) and diadenosine tetraphosphate (AppppA), b [...]	8-oxoguanine DNA glycosylase.	0.660

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