aptx protein (Takifugu rubripes) - STRING interaction network

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aptx

Aprataxin; DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined. Also able to hydrolyze adenosine 5'-monophosphoramidate (AMP- NH(2)) and diadenosine tetraphosphate (AppppA), b [...] (356 aa)

Predicted Functional Partners:

LOC115250498

0.945

LOC101066034

0.945

tdp1

0.914

xrcc4

0.900

hus1

0.894

parp1

0.894

APLF

0.881

parp2

0.872

lig3

0.854

tonsl

0.827

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APLF	LOC101066034	ENSTRUP00000048644	ENSTRUP00000070761	Aprataxin and PNKP like factor.	DNA repair protein XRCC1.	0.940
APLF	LOC115250498	ENSTRUP00000048644	ENSTRUP00000007413	Aprataxin and PNKP like factor.	X-ray repair complementing defective repair in Chinese hamster cells 1.	0.940
APLF	aptx	ENSTRUP00000048644	ENSTRUP00000024613	Aprataxin and PNKP like factor.	Aprataxin; DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined. Also able to hydrolyze adenosine 5'-monophosphoramidate (AMP- NH(2)) and diadenosine tetraphosphate (AppppA), b [...]	0.881
APLF	hus1	ENSTRUP00000048644	ENSTRUP00000012193	Aprataxin and PNKP like factor.	Checkpoint protein; Belongs to the HUS1 family.	0.750
APLF	lig3	ENSTRUP00000048644	ENSTRUP00000027352	Aprataxin and PNKP like factor.	DNA ligase.	0.983
APLF	parp1	ENSTRUP00000048644	ENSTRUP00000049295	Aprataxin and PNKP like factor.	Poly [ADP-ribose] polymerase.	0.977
APLF	parp2	ENSTRUP00000048644	ENSTRUP00000027488	Aprataxin and PNKP like factor.	Poly [ADP-ribose] polymerase.	0.968
APLF	tdp1	ENSTRUP00000048644	ENSTRUP00000015997	Aprataxin and PNKP like factor.	Tyrosyl-DNA phosphodiesterase 1.	0.963
APLF	xrcc4	ENSTRUP00000048644	ENSTRUP00000010998	Aprataxin and PNKP like factor.	Uncharacterized protein.	0.895
LOC101066034	APLF	ENSTRUP00000070761	ENSTRUP00000048644	DNA repair protein XRCC1.	Aprataxin and PNKP like factor.	0.940
LOC101066034	aptx	ENSTRUP00000070761	ENSTRUP00000024613	DNA repair protein XRCC1.	Aprataxin; DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined. Also able to hydrolyze adenosine 5'-monophosphoramidate (AMP- NH(2)) and diadenosine tetraphosphate (AppppA), b [...]	0.945
LOC101066034	hus1	ENSTRUP00000070761	ENSTRUP00000012193	DNA repair protein XRCC1.	Checkpoint protein; Belongs to the HUS1 family.	0.434
LOC101066034	lig3	ENSTRUP00000070761	ENSTRUP00000027352	DNA repair protein XRCC1.	DNA ligase.	0.987
LOC101066034	parp1	ENSTRUP00000070761	ENSTRUP00000049295	DNA repair protein XRCC1.	Poly [ADP-ribose] polymerase.	0.933
LOC101066034	parp2	ENSTRUP00000070761	ENSTRUP00000027488	DNA repair protein XRCC1.	Poly [ADP-ribose] polymerase.	0.843
LOC101066034	tdp1	ENSTRUP00000070761	ENSTRUP00000015997	DNA repair protein XRCC1.	Tyrosyl-DNA phosphodiesterase 1.	0.930
LOC101066034	xrcc4	ENSTRUP00000070761	ENSTRUP00000010998	DNA repair protein XRCC1.	Uncharacterized protein.	0.444
LOC115250498	APLF	ENSTRUP00000007413	ENSTRUP00000048644	X-ray repair complementing defective repair in Chinese hamster cells 1.	Aprataxin and PNKP like factor.	0.940
LOC115250498	aptx	ENSTRUP00000007413	ENSTRUP00000024613	X-ray repair complementing defective repair in Chinese hamster cells 1.	Aprataxin; DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined. Also able to hydrolyze adenosine 5'-monophosphoramidate (AMP- NH(2)) and diadenosine tetraphosphate (AppppA), b [...]	0.945
LOC115250498	hus1	ENSTRUP00000007413	ENSTRUP00000012193	X-ray repair complementing defective repair in Chinese hamster cells 1.	Checkpoint protein; Belongs to the HUS1 family.	0.434

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