Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
cul3Cullin 3a; Belongs to the cullin family. (767 aa)    
Predicted Functional Partners:
spopl
Speckle type BTB/POZ protein like b.
   
 0.995
SPOP
Speckle type BTB/POZ protein.
   
 0.995
arfgef1-2
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited).
   
 0.993
LOC115248454
RING-box protein 1.
    
 0.992
LOC101079814
Ring-box 1, E3 ubiquitin protein ligase.
    
 0.992
klhl20
Kelch-like family member 20.
    
 0.990
cops4
COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis).
    
 0.989
kbtbd8
Kelch repeat and BTB (POZ) domain containing 8.
    
 0.989
klhl22
Kelch-like family member 22.
    
 0.987
cand1
Cullin-associated and neddylation-dissociated 1.
   
 0.986
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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