STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC101065551Cytochrome P450, family 7, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (457 aa)    
Predicted Functional Partners:
LOC101077849
Cholesterol 25-hydroxylase like 2; Belongs to the sterol desaturase family.
   
 0.976
LOC101065133
Cholesterol 25-hydroxylase like 1, tandem duplicate 2; Belongs to the sterol desaturase family.
   
 0.976
hsd3b7
Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase; Belongs to the 3-beta-HSD family.
   
 0.973
hsd3b1
Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; Belongs to the 3-beta-HSD family.
   
 0.973
LOC101077007
Cholesterol 25-hydroxylase like 3; Belongs to the sterol desaturase family.
   
 0.968
LOC101063139
Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]
    
 0.949
LOC101069976
Si:ch211-113j14.1; Belongs to the cytochrome P450 family.
    
 0.934
LOC101063777
Si:dkey-91i10.3; Belongs to the cytochrome P450 family.
    
 0.934
LOC101062671
Cytochrome P450, family 27, subfamily A, polypeptide 7; Belongs to the cytochrome P450 family.
    
 0.934
LOC101073052
Sulfotransferase; Belongs to the sulfotransferase 1 family.
     
 0.910
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.