STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC101076043Insulin receptor substrate 2a. (1054 aa)    
Predicted Functional Partners:
LOC101074083
Tyrosine-protein kinase receptor.
   
 0.985
grb2
Growth factor receptor-bound protein 2b.
    
 0.984
LOC101063427
Tyrosine-protein kinase receptor.
    
 0.980
LOC101061204
Uncharacterized protein.
    
 0.979
LOC101074430
Tyrosine-protein kinase receptor.
   
 0.974
LOC101079603
Tyrosine-protein kinase receptor.
    
 0.974
mtor
Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.
    
 0.960
socs3
Suppressor of cytokine signaling 3a.
    
 0.951
ptpn1
Tyrosine-protein phosphatase non-receptor type.
    
 0.926
ikbkb
Inhibitor of nuclear factor kappa B kinase subunit beta.
    
 0.925
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.